Naloxone is a drug that can temporarily reverse an opioid overdose.

The Ontario Naloxone Program distributes injectable and nasal spray naloxone kits through participating community-based organizations to:

  • individuals at risk of opioid overdose
  • the individual’s friends and family

Through participating pharmacies, the Ontario Naloxone Program for Pharmacies distributes injectable and nasal spray naloxone kits to:

  • individuals at risk of opioid overdose
  • the individual’s family and friends
  • people in a position to care for at risk individuals

Program eligibility

The following organizations, centres and programs are eligible to participate in the Ontario Naloxone Program:

  • Needle Syringe Programs
  • Hepatitis C programs
  • public health units
  • Aboriginal Health Access Centres
  • AIDS service organizations
  • Community Health Centres
  • outreach programs
  • withdrawal management programs
  • shelters
  • hospital emergency departments, urgent care centres and inpatient units
  • police, fire services and St. John Ambulances Branches are eligible to receive naloxone for use when responding to opioid overdoses

To participate in the Ontario Naloxone Program, your organization, centre or program must:

  • be formally incorporated as an organization
  • reach individuals at risk of opioid overdose, and their friends and family
  • have demonstrated staffing capacity to manage distribution and training with clients, inventory and reporting requirements

All community pharmacies interested in participating in distributing naloxone kits are eligible to participate in the Ontario Naloxone Program for Pharmacies (ONPP).

Organizations that are not eligible to receive publicly funded naloxone through the Ontario Naloxone Program and Ontario Naloxone Program for Pharmacies are able to purchase it directly from the manufacturers.

How to apply

To apply to the Ontario Naloxone Program, your organization, centre or program administrator should contact your local public health unit.


To participate in the Ontario Naloxone Program for Pharmacies, pharmacies should review the Executive Officer (EO) EO materials (such as, EO notice and FAQs) outlining all the necessary information to participate in the ONPP program at the following link: Executive Officer Communications


If you require this information in an alternative format, please contact publicdrugprgrms.moh@ontario.ca. We will:

  • acknowledge your request within three business days
  • provide you with the content within 15 business days

How to be added to the naloxone kit locator map

Pharmacies and community-based organizations, centres and programs are encouraged to review the current map locator tool to check if they are listed. Access the map locator tool, which is updated regularly.

If your pharmacy participates in the Ontario Naloxone Program for Pharmacies and would like to be added to the map locator tool, please send an email request to: PublicDrugPrgrms.moh@ontario.ca.

If your pharmacy would like to be removed from the map locator tool, please send an email request to: PublicDrugPrgrms.moh@ontario.ca.

For either request, please provide:

  • your name
  • your pharmacy name and full address, including contact information (for example, email, phone, fax)

Naloxone administration training

Ontario Naloxone Program

Your organization, centre or program staff is responsible for training eligible individuals how to recognize and respond to an opioid overdose and how to administer naloxone.

Public Health Units provide guidance on this training.

Training will include how to recognize an opioid overdose and 5 steps to respond to an opioid overdose.

If you are with someone who is having an opioid overdose

  1. Shout their name and shake their shoulders
  2. Call 9-1-1 if they are unresponsive
  3. Give naloxone
    1. if using an injectable kit - inject 1 vial or ampoule (a small glass container) (0.4 mg/1 ml) of naloxone into their arm or leg
    2. if using a nasal spray kit - lay the person on their back, insert the tip of nozzle into one nostril and press the plunger firmly
  4. Perform rescue breathing and/or chest compressions
  5. If there is no improvement after 2-3 minutes, repeat steps 3 and 4. Stay with them
During the COVID-19 pandemic, the rescue breathing barrier included in naloxone kits can be used as a layer of protection during rescue breathing but may not prevent transmission of infection on its own. It is recommended that individuals responding to an opioid overdose are fully vaccinated against COVID-19 including any recommended booster doses to help prevent transmission.

If the person begins breathing on their own, or if you have to leave them on their own, put them in the recovery position.

The illustration shows a person lying on their right side with their left arm bent in front of them and their left hand under their right ear to support their head. The head is tilted back slightly to open the airway. The right leg is straight and the left leg is bent in front of it with the knee touching the ground. This is to stop the body from rolling onto its stomach.

Stay until the ambulance arrives in case paramedics need help or information, or the overdose symptoms return. With more powerful opioids (fentanyl and carfentanil) there is a possibility that a person will overdose again even after they have been given naloxone and even if they don’t use more drugs.

Ontario Naloxone Program for Pharmacies

For those who receive a naloxone kit for the first time, a pharmacist is expected to provide the necessary professional training to the eligible person.

Replacement kits are available without training provided that the individual had previously received professional training, including from a ministry naloxone program or elsewhere.

What’s in a naloxone kit

Each nasal spray naloxone kit includes:

  • 1 hard case (for example, a zippered hard black case with red “naloxone” cross)
  • 2 doses of naloxone hydrochloride intra-nasal spray (4 mg/0.1 ml))
  • 1 rescue breathing barrier
  • 1 pair of non-latex gloves
  • 1 card that identifies the person trained to give the naloxone
  • 1 insert with instructions (English and French)

Each injectable naloxone kit includes:

  • 1 hard case (for example, a zippered hard black case with red “naloxone” cross)
  • 2 (0.4 mg/1 ml) vials or ampoules (a small glass container) of naloxone
  • 2 safety-engineered syringes with 25g, 1” needles attached
  • 2 alcohol swabs
  • 2 devices (known as “breakers,” “snappers,” or “openers” for opening ampoules safely)
  • 1 rescue breathing barrier
  • 1 pair of non-latex gloves
  • 1 card that identifies the person who is trained to give the naloxone
  • 1 insert with instructions (English and French)

Types of naloxone

Both injectable and nasal spray naloxone are effective at reversing the effects of an opioid overdose.

Both the Ontario Naloxone Program and Ontario Naloxone Program for Pharmacies provide Ontarians with options based on their preference.

Information for participating pharmacies

Through the Ontario Naloxone Program for Pharmacies (ONPP), participating pharmacies can distribute publicly-funded injectable naloxone kits or intra-nasal naloxone spray kits.

Pharmacies are to procure naloxone and the required supplies to assemble the injectable naloxone kit and/or pre-assembled kits through their usual suppliers. The naloxone kit will be assembled by a pharmacist or a person under the supervision of a pharmacist.

The Ontario Pharmacists Association has also compiled a list of the required kit components, as well as some suppliers for these items, in the event that pharmacists are unable to procure some or all of the elements through their usual suppliers. See details on the kit contents.

The list can be accessed at opatoday.com/naloxone.

Number of naloxone kits that can be distributed through the ONPP at one time

Through the Ontario Naloxone Program for Pharmacies (ONPP), eligible individuals may receive up to two naloxone kits at a time on an individual basis.

For the ONPP, it is up to the pharmacist’s professional judgement on providing naloxone kits.

Requirement to show Ontario health card at a participating pharmacy to receive a naloxone kit

An Ontario health card is no longer required to receive free naloxone kits from a participating pharmacy. More specifically, pharmacists may provide naloxone kits to Ontarians who meet the eligibility criteria and who do not have an Ontario health card or to those who do not wish to provide identification.

The intent is for pharmacists to ask for a health card when distributing naloxone kits. Should the individual not have a health card or does not wish to present it, pharmacists can still provide a naloxone kit based on their professional judgement.

Expired or unused naloxone kits

Naloxone kits that are expired or unused can be brought to any pharmacy for safe disposal in Ontario.

Individuals, including patients, are encouraged to talk to their pharmacist about disposal of unused or expired medications, that may include unused or expired naloxone kits. Most Ontario pharmacies are able to accept such medications, as well as sharps (for example, needles and syringes).

Naloxone kits for individuals using prescription opioids

Many people use prescription opioids safely. It is important that you discuss overdose risks with your patients. If you have concerns about a particular patient who may be at risk of overdosing, you can direct them to the government’s naloxone programs web page to find the nearest naloxone kit distribution site.

Legal protections

Canada’s Good Samaritan Drug Overdose Act, provides some legal protection for people seeking emergency help during an overdose.

In addition, Ontario’s Good Samaritan Act, 2001 provides some legal protection to individuals from civil liability in certain cases, such as if a person administers naloxone to a person experiencing an overdose in certain situations.

Provincial regulations regarding the administration and/or distribution of naloxone in Ontario

Injectable naloxone (0.4 mg/1 ml) and nasal spray naloxone (4 mg/0.1 ml) are behind-the-counter products available without a prescription in Ontario, when indicated for emergency use for opioid overdose. The dispensing of naloxone in an Ontario pharmacy is subject to the Drug and Pharmacies Regulation Act and the policies of the Ontario College of Pharmacists.


Download a free poster informing your clients or patients about the nearest place to get a naloxone kit.

In-person substance use and alcohol support


Ontario funds a wide range of community-based mental health and addictions programs and services through the Ontario Health regions. You can find more information about services in communities across Ontario through ConnexOntario.

ConnexOntario can be reached either by dialing 811, the new Health Connect Ontario number, or you can contact Connex Ontario directly at:

Youth Wellness Hubs Ontario

Youth Wellness Hubs Ontario offers walk-in access to primary care, addictions and mental health services for people aged 12 to 25. These core clinical services, delivered by the youth wellness team, are co-located with a range of other services and supports in the fields of education, employment, training, housing and other community and social services.

Currently, there are 14 sites in operation: Chatham-Kent, Eastern Champlain region, Haliburton, Kenora, Malton, Niagara region, North Simcoe, Scarborough, Central Toronto, East Toronto, Windsor, Timmins, Renfrew and Guelph. More information on YWHO including specific site locations can be found online.

RAAM clinics

Visit a Rapid Access Addiction Medicine (RAAM) clinic. RAAM clinics help people seeking treatment for substance use issues, including opioids, alcohol and other substances. You do not need a referral or appointment to visit a RAAM clinic.

Doctors and counsellors at RAAM clinics help stabilize clients before referring them to primary care and other longer-term community mental health and addictions services and supports.
RAAM clinics can provide:

  • assessments and diagnoses for substance use disorders
  • treatment options
  • prescriptions for medications to help with cravings and withdrawal symptoms
  • counselling
  • overdose prevention education

All clinics are:

  • accessible on a walk-in basis, with patients typically seen within a few days of contacting the clinic
  • client-centered
  • non-judgmental

RAAM locations can be found online through the Ontario.ca website.